Wednesday, November 26, 2008

Apidra Update

I've now been using Apidra for over a month. I have to admit, it's a very fast acting insulin compared to Novolog. It has taken a couple of weeks to understand how it reacts to my food and activities.

For my breakfast and lunch times, I have been able to tune my dosage quite effectively. However, my dinners have been giving me some trouble. For the most part, my breakfast and lunches are very standardized. My dinner are a bit more variable. Listed below is a situation that I've been encountering:

6:00pm - Apidra bolus and begin eating dinner (normal bolus)
6:30pm - Blood sugar begins to drop
7:00pm - blood sugar begins to rise dramatically (so I bolus again)
8:00pm - blood sugar begins to stabilize nicely

In doing some research on the insulin curve for Apidra, it reacts very fast, and can be on it's downward peak after one hour. This matches exactly to my situation above.

To fix this, I've now been doing a dual-wave bolus, where I'm lowering my initial bolus and spreading out the remainder for about an hour. This has been working better. Anyone else using Apidra?

3 Comments:

At December 8, 2008 at 12:17 PM , Anonymous Anonymous said...

Hi,I've been using Apidra for 3 weeks and am having the same problem,my BS seems to rise hugely after about 90 mins.I've just started experimenting with the dualwave and extended bolusing....hindered by a sinus infection! I'm finding that my C:I ratio is about 8-10:1 which is lower than it was on Novorapid,everyone I've spoken to uses loads less not more...puzzling me at the mo! Basals are largely ok and corrections are great,just the bolusing that's a problem.

 
At November 21, 2009 at 8:43 AM , Blogger Sayer Strauch said...

I've been using Apidra for a couple of years or so now. My experience is that Apidra is a fast-acting insulin and handles meal-times well. It was recommended to me, in part, because it was said to better guard against lows. It was also said to be better for those who are active and exercise frequently. It also was said not to result in nearly as much a skin reaction at infusion sites.

I haven't encountered the rapid rise after meals. One big factor that helps my body stay away from rapid rises in bg after meals is eating a relatively alkaline diet.

 
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