Wednesday, November 26, 2008

Apidra Update

I've now been using Apidra for over a month. I have to admit, it's a very fast acting insulin compared to Novolog. It has taken a couple of weeks to understand how it reacts to my food and activities.

For my breakfast and lunch times, I have been able to tune my dosage quite effectively. However, my dinners have been giving me some trouble. For the most part, my breakfast and lunches are very standardized. My dinner are a bit more variable. Listed below is a situation that I've been encountering:

6:00pm - Apidra bolus and begin eating dinner (normal bolus)
6:30pm - Blood sugar begins to drop
7:00pm - blood sugar begins to rise dramatically (so I bolus again)
8:00pm - blood sugar begins to stabilize nicely

In doing some research on the insulin curve for Apidra, it reacts very fast, and can be on it's downward peak after one hour. This matches exactly to my situation above.

To fix this, I've now been doing a dual-wave bolus, where I'm lowering my initial bolus and spreading out the remainder for about an hour. This has been working better. Anyone else using Apidra?

Wednesday, November 19, 2008

Test Driving Apidra insulin

At my last visit, my endo gave me a bottle of Apidra insulin to try out. I've been using novolog for many years, and have had my ups and downs with it. I've noticed the following things with using Novolog:
  • When changing infusion sets, I always get a 2-4 hour period that the insulin doesn't seem to absorb well.
  • Novolog doesn't act fast enough during my bolus
  • After a couple of days, I've noticed that sites become less aborbant to the insulin

My endo recommended apidra to help with some of these reasons. After Apidra for the last 5 days, I am very pleased. It appears to act much quicker than Novolog and my infusion sites have been more stable.

Anyone else have opinions on Apidra?